Course
General Information
| Course Id | KIM425062 |
| Course | Medicinal Chemistry |
| Curriculum | S1 KIMIA 2020 |
| Credit | 2 |
| Course Type | elective |
| Description | "THE LEARNING ACHIEVEMENT OF THIS COURSE IS THAT STUDENTS ARE ABLE TO ANALYZE THE DRUG DEVELOPMENT PROCESS BY TAKING INTO ACCOUNT THE FACTORS THAT AFFECT THE PHARMACOKINETICS AND PHARMACODYNAMICS OF DRUGS, AS WELL AS DRUG BINDING WITH THE RECEPTORS SO THAT THEY CAN DESIGN DRUG DESIGNS. THE MATERIAL INCLUDES THE MEANING, CONCEPT, BENEFITS OF LEARNING MEDICINAL CHEMISTRY; HISTORY OF DRUG DISCOVERY; DRUG DEVELOPMENT PROCEDURES; RELATIONSHIP OF STRUCTURE, PHYSICAL AND CHEMICAL PROPERTIES WITH ADME; THE RELATIONSHIP OF SOLUBILITY AND PARTITION COEFFICIENT TO ACTIVITY; DRUG METABOLIC PROCESSES; THE FERGUSON PRINCIPLE AND DRUG ACTION MODEL; INFLUENCE OF ISOMERS ON BIOLOGICAL ACTIVITY; THE HKSA APPROACH; DRUG AND RECEPTOR INTERACTIONS; CHEMICAL BONDS INVOLVED IN BINDING DRUGS AND RECEPTORS; BIOACTIVATION AND BIOINACTIVATION OF DRUG MOLECULES; MOLECULAR MODIFICATION AND ANTIOXIDANT DRUG DESIGN; AND MOLECULAR MODIFICATION AND CANCER DRUG DESIGN. " |